Breast cancer-related lymphedema (BCRL) is one of the most common chronic complications following breast cancer treatment. This study enrolls breast cancer patients who are required to undergo axillary lymph node dissection and postoperative adjuvant radiotherapy. Based on patients' preferences, they will be assigned to receive either immediate distal lymphaticovenous anastomosis (ID-LVA) following axillary lymph node dissection (experimental group) or not (control group). The study aims to evaluate the safety and efficacy of ID-LVA in preventing breast cancer-related upper limb lymphedema.
Age >=18 years;
Female;
Pathologically confirmed invasive breast cancer;
Unilateral breast cancer;
Currently participating in other clinical trials that, in the investigator's judgment, may affect upper limb lymphatic drainage.
No definitive indication for axillary lymph node dissection or adjuvant radiotherapy after neoadjuvant therapy.
Pregnant or lactating women.
Patients undergoing concurrent autologous tissue flap breast reconstruction or chest wall repair.