Supplementation With Sirtuin Activators in Women With Increased Body Weight

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age40-65
SponsorPoznan University of Life Sciences

About this trial

The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are:

Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing?

Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status.

Participants will:

Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.

Eligibility criteria

Qualifiers

females

age: 40-65 years

overweight or obese: BMI >25 kg/m2

Disqualifiers

males

BMI < 25 kg/m2

sirtuin activators administration for 3 months prior to study

pregnancy or breastfeeding

Trial design

Treatments tested in this trial

  • Sirtuin activators
  • Placebo

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Poznan University of Life Sciences

Lead sponsor

Poznan University of Medical Sciences

Collaborator

NutroPharma

Collaborator