About this trial
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are:
Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing?
Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status.
Participants will:
Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.
Eligibility criteria
Qualifiers
females
age: 40-65 years
overweight or obese: BMI >25 kg/m2
Disqualifiers
males
BMI < 25 kg/m2
sirtuin activators administration for 3 months prior to study
pregnancy or breastfeeding
Trial design
Treatments tested in this trial
- Sirtuin activators
- Placebo
Treatment groups
Sponsors and collaborators
Poznan University of Life Sciences
Lead sponsor
Poznan University of Medical Sciences
Collaborator
NutroPharma
Collaborator