About this trial
This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression disorder, expressive-supportive vs. emotion-focused treatment. Their ability to benefit from treatment based on their pre-treatment levels of insight and emotional processing will be examined. This is a four-month protocol, with a 2 year follow up period.
Eligibility criteria
Qualifiers
Meeting major depressive disorder diagnostic criteria using the structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders-5 and scoring more than 14 on the 17-item Hamilton rating scale for depression at two evaluations (one week apart) (Hamilton, 1967).
If on medication, patients' dosage must be stable for at least three months prior to entering the study, and they must be willing to maintain stable dosage for the duration of treatment
Age between 18 and 65
Hebrew language fluency
Disqualifiers
Current risk of suicide or self-harm
current substance abuse disorders
current or past schizophrenia or psychosis, bipolar disorder, or severe eating disorder requiring medical monitoring
history of organic mental disease
Trial design
Treatments tested in this trial
- Supportive-expressive treatment
- Emotions-Focused treatment
Treatment groups
Sponsors and collaborators
University of Haifa
Lead sponsor
Israel Science Foundation
Collaborator