Surgical Ablation of AF Efficacy Trial
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorPopulation Health Research Institute
About this trial
SAFE is an international multicentre RCT of concomitant surgical atrial fibrillation (AF) ablation in patients with paroxysmal or persistent AF undergoing cardiac surgery.
Eligibility criteria
Qualifiers
Age ≥ 18 years;
Undergoing a clinically indicated cardiac surgical procedure: CABG, AVR, ascending aorta replacement, or combinations thereof;
Documented history of paroxysmal or persistent AF
Provide informed consent
Disqualifiers
Dominant atrial arrhythmia is atrial flutter;
Documented left atrial diameter ≥ 6 cm;
Previous cardiac surgery requiring opening of the pericardium;
Heart transplant
Trial design
Treatments tested in this trial
- Surgical Atrial Fibrillation Ablation
Treatment groups
2,000 Participants
are divided into 2 treatment groupsSponsors and collaborators
Population Health Research Institute
Lead sponsor
Hamilton Health Sciences Corporation
Collaborator
Source ClinicalTrials.gov