Surveillance for Multifocal GGNs
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorFudan University
About this trial
This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) with the identification number ECTOP-1021. The primary objective of the study is to assess the overall survival of patients with multifocal ground-glass opacities by employing a active surveillance approach rather than opting for surgical resection.
Eligibility criteria
Qualifiers
Presence of three or more GGNs (bilateral lesions are permitted).
All lesions have remained stable without regression or enlargement for at least 3 months.
The dominant lesion (the lesion with the largest maximum tumor diameter) has a maximum tumor diameter >=0.6cm and <=2cm.
CTR <=0.25 in all lesions.
Disqualifiers
History of any prior malignancies within the past 5 years.
History of lung surgery.
History of interstitial pneumonia, pulmonary fibrosis or other severe pulmonary diseases.
Presence of severe or uncontrolled diseases that may possibly reduce the 10-year life expectancy.
Trial design
Treatments tested in this trial
- Watchful waiting
Treatment groups
370 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov