Surviving the Pediatric Intensive Care Unit (PICU)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age28-16
SponsorKK Women's and Children's Hospital

About this trial

Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient/survivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disruptions in their daily routines, all of which can contribute to long-term negative outcomes if unaddressed. Thus, this study consists of two cohorts to understand the long-term physical, cognitive, and psychological outcomes in PICU survivors and their families, and the short-term impacts on siblings of critically ill children.

Eligibility criteria

Qualifiers

Between 28 days - 16 years of age at PICU admission

Have an expected PICU stay > 48 hours*

Healthy children (aged 4 -16 years old) with critically ill sibling between 28 days - 16 years of age at PICU admission

Has a critically ill sibling who has an expected PICU stay > 48 hours

Disqualifiers

Do-Not-Resuscitate status

Lack of informed consent

Prior enrolment in this study

Children of critically ill sibling with Do-Not-Resuscitate status

Trial design

Treatments tested in this trial

  • This is a non-interventional study.

Treatment groups

404 Participants
are divided into 2 treatment groups

Sponsors and collaborators

KK Women's and Children's Hospital

Lead sponsor

National University Hospital, Singapore

Collaborator

Duke-NUS Graduate Medical School

Collaborator

Singapore Clinical Research Institute

Collaborator