The goal of this study is to perform a randomized trial to compare a new through-the-scope suturing system and conventional clips for closure of defect after ESD for 30-60 mm colonic polyps. More precisely, the hypothesis posits that the new through-the-scope suturing system can achieve higher complete closure rates in a shorter time in comparison to conventional clips.
Patient suffering from 30-60 mm colonic polyps with indication of ESD
Male or female patients aged > 18 years' old
Patients able to fill in questionnaires written in Italian
Failure of endoscopic resection
Suspicion of deep submucosal cancer by analysis of pit pattern (KUDO Vn)
Polyp involving the appendix deeply (type 2 or 3 according to Toyonaga classification)
Polyp inside the ileo-cecal valvula.