Swallowing Impairments in Adults With and Without Alzheimer's Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60+
SponsorVanderbilt University Medical Center
About this trial
This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involving the primary caregivers of individuals with Alzheimer's that are enrolled in the study to better understand the impact of swallowing impairments on the primary caregivers of those with Alzheimer's Disease.
Healthy adults and individuals with Alzheimer's disease will:
* undergo tests of cough and swallow function * undergo tests of grip and tongue strength * complete questionnaires
Caregivers of individuals with Alzheimer's disease will also complete questionnaires.
Eligibility criteria
Qualifiers
adult ≥60 years old
diagnosis of AD by a neurologist (confirmed with imaging, spinal tap, behavioral testing)
no prior history of other neurological diseases (aside from stroke which has resolved with no current symptoms)
no prior history of respiratory diseases
Disqualifiers
individual <60 years old
Diagnosis of another type of dementia
History of neurological/respiratory diseases
History of head and neck surgery/head and neck cancer/radiation to head and neck region
Trial design
Treatments tested in this trial
- Not listed
Trial groups
240 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov