SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis. 2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels. 3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

Eligibility criteria

Qualifiers

Patients diagnosed as PsO by a dermatologist according to PASI score.

Patients diagnosed as PsA by rheumatologist according to CASPAR classification criteria for psoriatic arthritis

Adult patients of both sexes with an average > 18 years

Disqualifiers

Patients with a history of metabolic disease affecting tendons.

Patients with history of surgery, injury or trauma of patellar and/or Achilles tendon.

Patients with other rheumatological diseases.

Patients below 18.

Trial design

Treatments tested in this trial

  • Musculoskeletal Ultrasound Device

Treatment groups

No treatment groups listed

Sponsors and collaborators