About this trial
Purpose: To establish a whole food, egg, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development. There will be 84 breastfeeding dyads, 3 months postnatal.
Mothers will be randomized to a whole egg or egg white (due to lack of an appropriate control food). Initial diet intake will be screened using the NDSR. Participants will come to the lab 3 times across 3 months (age 3 months, 4.5 months, and 6 months). Milk, saliva, and plasma will be collected from the mother, while saliva and plasma (heel stick) are collected from the infant. Diet data will be collected at each visit. The infant will complete a recognition memory test using electrophysiology at 6 months as well as the Bayley Scales of Infant Development at 4.5 months. The mother will complete a temperament questionnaire at 3 months and 6 months.
Eligibility criteria
Qualifiers
infant is 12-15 weeks of age at enrollment
healthy, lactating mother age 18-35
gave birth at >38 weeks gestation without remarkable incident
consuming <=50% of the recommended amounts of 2 of the 3, DHA, choline, and lutein
Disqualifiers
infant with diagnosis or documented suspicion of developmental delay
egg allergy or family history of egg allergy
gestational diabetes
any documented seizure activity
Trial design
Treatments tested in this trial
- Whole Egg Powder
- Egg White Powder
Treatment groups
Sponsors and collaborators
University of North Carolina, Chapel Hill
Lead sponsor
Egg Nutrition Center
Collaborator