Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Nice
About this trial
The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.
Eligibility criteria
Qualifiers
Invasive mechanical ventilation for more than 48 hours
SpO2> 90% with FiO2 ≤40% and PEEP ≤5 cmH2O
Cough effectiveness on tracheal aspirations
Lack of hemodynamic instability and of disorders of consciousness
Disqualifiers
Age <18 years and pregnant women
Patients with a decision of not to resuscitate
Poor echogenicity
Severe mitral valve disease (leakage and/or stenosis, bioprosthesis)
Trial design
Treatments tested in this trial
- Spontaneous breathing trial
Treatment groups
250 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov