TACTIC Coronary Thrombus Aspiration With Cath Rx In Anterior Myocardial Infarction: A Randomized Control Trial.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorCeric Sàrl

About this trial

The aim of this study is to evaluate the impact of sustained thrombectomy with INDIGO ASPIRATION SYSTEM using CAT RX versus no thrombectomy during primary percutaneous coronary intervention (PPCI) on microvascular obstruction and infarct size, as measured by cardiovascular magnetic resonance (CMR) between 3 and 5 days post PPCI, in patients with anterior STEMI

Eligibility criteria

Qualifiers

Age >18 and <75 years old

Acute anterior STEMI with ≥2 mm in two (2) or more contiguous anterior leads or ≥4 mm total ST-segment deviation sum in the anterior leads V1-V4 AND anterior wall motion abnormality noted on a diagnostic quality left ventriculogram or echocardiogram

Culprit lesion proximal or mid LAD at coronary angiography

TIMI thrombus grading > 3 or TIMI flow 0 after guidewire crossing the lesion.

Disqualifiers

Unable to give Informed consent.

Life expectancy < 1 year.

Contraindication to PCI

STEMI due to stent thrombosis

Trial design

Treatments tested in this trial

  • THROMBOASPIRATION WITH INDIGO SYSTEM

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Ceric Sàrl

Lead sponsor

European Cardiovascular Research Center

Collaborator