About this trial
The goal of this clinical trial is to evaluate whether an AI-powered digital brain health coaching intervention can improve modifiable brain health risk factors in community-dwelling adults aged 40 and above in Singapore.
The main question it aims to answer is: does the use of BLAZE, an AI-powered digital brain health coaching intervention, lead to a greater improvement in Brain Care Score (BCS) compared to usual care at 6 months?
Researchers will compare participants receiving BLAZE to those receiving usual care (waitlist control) to see if BLAZE leads to greater improvements in brain health risk factors, behavioural outcomes, quality of life, and cost-effectiveness.
Participants will:
* Be randomly assigned to either receive BLAZE immediately for 12 months or be placed on a waitlist receiving usual care for the first 6 months before receiving BLAZE for a further 6 months * Complete a series of assessments at baseline, 6 months, and 12 months including the Brain Care Score, physical function tests, cognitive assessments, quality of life measures, and lifestyle behaviour questionnaires * If assigned to the intervention group, interact with BLAZE via a WhatsApp-based platform that delivers personalised brain health recommendations, behavioural nudges, educational content, and goal-setting support based on their individual Brain Care Score profile
Eligibility criteria
Qualifiers
Community-dwelling adults
Aged 40 years and above at time of recruitment
Able to use a smartphone and smartphone applications
Able to provide written informed consent
Disqualifiers
Been diagnosed wotj dementia, neurocognitive disorder or any major psychiatric illness
Have severe sensory or physical disability precluding usage of the application
Terminal illness or expected survival of less than 12 months at point of recruitment
Trial design
Treatments tested in this trial
- BLAZE (Brain health Lifestyle Action with personaliZed Engagement)
Treatment groups
Sponsors and collaborators
Alexandra Hospital
Lead sponsor
National University Hospital, Singapore
Collaborator
National University Polyclinics, Singapore
Collaborator