About this trial
This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants. The purpose of the study is to determine if there is a benefit to target fortifying donor breast milk in the preterm population. The investigators hypothesize that infants receiving targeted fortification of donor breast milk will have improved growth compared to infants receiving standard fortification of donor breast milk.
Eligibility criteria
Qualifiers
Premature infants born </= 30 weeks gestational age
Birth Weight </= 1500 grams
Disqualifiers
Parents do no consent to donor milk
Confounders for poor growth such as congenital heart disease, GI diagnoses such as gastroschisis and omphalocele, and or major congenital anomalies
Grade III or IV intraventricular hemorrhage diagnoses prior to randomization
Small for gestational age (<3% on Fenton Growth Curve)
Trial design
Treatments tested in this trial
- Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid
- Similac Liquid Protein Fortifier
- Nestle Microlipid
- Medica Nutrition SolCarb
- Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification)
- Similac Liquid Protein Fortifier (Targeted Fortification)
- Nestle Microlipid (Targeted Fortification)
- Medica Nutrition SolCarb (Targeted Fortification)
- Analysis with Miris (AB) Human Milk Analyzer