Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-80
SponsorUniversity of North Carolina, Chapel Hill

About this trial

The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk. Using metronomes is commonly used in clinics, but the investigators will be using a combination of slow and fast frequencies to alter the way that people walk. The use of a slower frequency metronome on the treadmill is intended to help participants take larger steps. The use of a faster frequency metronome while walking overground is intended to help participants take faster steps.This will take place over 12 training sessions. Each session will be about an hour. It will include some walking tests and pictures of the brain (using MRI) before and after training.

Eligibility criteria

Qualifiers

idiopathic Parkinson's disease (Hoehn and Yahr Stage 2-3)

self-report the ability to walk uninterrupted for 10 minutes both overground and on a treadmill without therapist assistance

comfortable gait speed > 0.4 m/s and < 1.2 m/s

normal (or corrected to normal [i.e., hearing aid]) hearing

Disqualifiers

contraindications to MRI (e.g., metal implants, claustrophobia, etc)

cognitive deficits (Montreal Cognitive Assessment [MoCA] < 26)

concurrent Physical Therapy

have undergone deep brain stimulation surgery

Trial design

Treatments tested in this trial

  • Gait training without rhythmic auditory cues
  • TRAC
  • dTRAC

Treatment groups

45 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University of North Carolina, Chapel Hill

Lead sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator