Targeted Nutrient Supplement in COPD (NUTRECOVER-trial)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMaastricht University Medical Center
About this trial
The overall objective is to investigate the efficacy of targeted nutrient supplementation on daily physical activity level as well as generic health status in patients with COPD. Additionally the investigators aim to investigate the relative effect of targeted nutrient supplementation on the recovery after hospitalization for a COPD exacerbation. The secondary objective is to investigate the effect of targeted nutrient supplementation on mental health, physical performance, blood markers, patient related outcomes and gut health. Additionally, a secondary objective is to compare the gut microbiome composition of patients with COPD compared to healthy controls.
Eligibility criteria
Qualifiers
COPD patients with moderate to very severe disease stage according to GOLD criteria (i.e. GOLD stage II-IV);
Medically stable.
Disqualifiers
Age <18 years;
Allergy or intolerance to components of the study product;
Not willing or not able to quit vitamin D or fatty acid supplement intake;
Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements (e.g. leg amputation) or patients suffering from other acute or unstable chronic diseases that will compromise the study outcome (e.g. active cancer requiring treatment);
Trial design
Treatments tested in this trial
- Targeted nutrient supplementation (Long-drink)
- Placebo supplement
- Counselling
Treatment groups
166 Participants
are divided into 3 treatment groupsSponsors and collaborators
Maastricht University Medical Center
Lead sponsor
Nutricia Research
Collaborator
Source ClinicalTrials.gov