About this trial
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.
Eligibility criteria
Qualifiers
aged 25-85
must be greater than 6 months post-stroke
must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production
must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage
Disqualifiers
comorbid neurological disease.
damage to the anterior right hemisphere.
significant mood disorder.
substance/alcohol dependence or abuse within the past year
Trial design
Treatments tested in this trial
- Active Comparator: Experimental: Active cathodal tDCS + language training
- Sham Comparator: Placebo cathodal tDCS + Speech and language
Treatment groups
Sponsors and collaborators
University of New Mexico
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of General Medical Sciences (NIGMS)
Collaborator
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator