Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-20
SponsorNorthwell Health
About this trial
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.
Eligibility criteria
Qualifiers
Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level
A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB).
Disqualifiers
Any DSM 5 Schizophrenia-Spectrum diagnosis
Non-English speaking
Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder)
Estimated IQ<70
Trial design
Treatments tested in this trial
- SCORES (Specific COgnitive Remediation with Support)
Treatment groups
54 Participants
are divided into 2 treatment groupsSponsors and collaborators
Northwell Health
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov