tDCS and Symptom Provocation in Treatment-Resistant OCD
ConditionObsessive - Compulsive Disorder
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorCentre Hospitalier Henri Laborit
About this trial
The goal of this clinical trial is to learn if symptom provocation before transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder (OCD) patients. The main question it aims to answer is:
Can symptom-provocation before tDCS improve therapeutic response in OCD patients ?
Researchers will compare the clinical outcomes of OCD patients having received, in one arm, tDCS and, in the other arm, patients having received tDCS preceded by symptom provocation to see if therapeutic response and various other clinical variables differ.
Eligibility criteria
Qualifiers
Diagnosis of Obsessive-Compulsive Disorder (OCD) according to DSM-5, with a duration ≥ 2 years.
Good insight, defined as a BABS score ≤ 18.
Chronic OCD, with either a Y-BOCS total score > 20 or a subscale score > 15.
failure of ≥ two adequate trials of SSRIs, or
Disqualifiers
Women of childbearing potential without effective contraception, or those unwilling to maintain abstinence or contraception.
Pregnancy or breastfeeding.
Compulsory psychiatric hospitalisation.
Legal guardianship or curatorship.
Trial design
Treatments tested in this trial
- tDCS session
- symptom provocation
Treatment groups
178 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov