TDCS Stimulation After Covid-19 Infection

ConditionCOVID-19
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorIstanbul Medipol University Hospital

About this trial

In this study, the effects of bilateral stimulation of the dorsolateral prefrontal cortex (DLPFC) with active tDCS (transcranial direct stimulation/transcranial direct stimulation) on neurocognitive (memory and executive) functions in patients with Covid-19 infection and subjective cognitive complaints, as well as resting-state fMRI In the case of dfMRI, it is aimed to examine the default mode network (DMN) and parietal memory network (PMN) inter- and intra-network connectivity alterations and the hippocampal region connectivity alterations and contribute to the relevant literature.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Have received a positive value from the COVID-19 RT-PCR test in the last 60 days and turned negative

Being between the ages of 18-50

21 days have passed since the disease onset date

Disqualifiers

Having any neurological or psychiatric disease

Trial design

Design model

Crossover

Treatments tested in this trial

  • Transcranial Direct Stimulation

    Procedure/Surgery

    2 mA, 20 min, 5 days

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: InterventionalActive comparator 1 intervention
Group B: ShamPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Montreal cognitive assessment

Cognition Test

Time frame
Before Treatment / 1 month after treathment
2

Cognition Test Material

clock drawing test, digit range test, verbal fluency test, stroop test, trail making test

Time frame
Before Treatment / 1 month after treathment
3

NPI

Cognition Test (Neuropsychiatric Inventory)

Time frame
Before Treatment / 1 month after treathment
4

Öktem Verbal Memory Processes Test

Cognition Test

Time frame
Before Treatment / 1 month after treathment

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Istanbul Medipol University Hospital

Lead sponsor

Alanya Alaaddin Keykubat University

Collaborator