TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-65
SponsorZhejiang University
About this trial
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients.
The primary question it seeks to answer is:
Does TEAS combined with triple antiemetics further reduce the incidence of PONV in high-risk subjects? Researchers will compare active TEAS with sham stimulation to determine whether the addition of TEAS to dexamethasone, palonosetron, and droperidol lowers the PONV rate beyond that achieved by the triple-drug prophylaxis alone.
Eligibility criteria
Qualifiers
Women scheduled for laparoscopic surgery ；
Aged 18-65 years；
ASA Class I-III；
Apfel score ≥ 3 (female sex, non-smoker, history of PONV and/or motion sickness).
Disqualifiers
Patients with a history of allergy to the investigational drug or contraindications；
Long-QT syndrome ；
Pregnancy, lactation, or menstruation ；
Current smoker；
Trial design
Treatments tested in this trial
- transcutaneous electrical acupoint stimulation
- Sham transcutaneous electrical acupoint stimulation
- triple antiemetic drugs
Treatment groups
780 Participants
are divided into 2 treatment groupsSponsors and collaborators
Zhejiang University
Lead sponsor
Jinhua Central Hospital
Collaborator
Huzhou Central Hospital
Collaborator
The First People's Hospital of Huzhou
Collaborator
Source ClinicalTrials.gov