About this trial
This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast cancer to receive all of their planned chemotherapy according to schedule and at the planned dose.
Eligibility criteria
Qualifiers
Women age >=65
Diagnosed with stage I-III invasive breast cancer
BMI between 18-50 kg/m2
Scheduled to begin at least 10 weeks of neoadjuvant or adjuvant cytotoxic chemotherapy for curative intent
Disqualifiers
Following a therapeutic diet for co-morbid disease where the THRIVE-65 diet would be contraindicated as assessed by the RD
Engaging in 2 or more sessions of strength training exercise per week over a period of at least 3 consecutive months over the past year
Engaging in aerobic activity at a level that includes competitive events (e.g., marathon, triathlon, running races) over the past year
Presence of medical conditions or medications that would prohibit participation in an exercise program
Trial design
Treatments tested in this trial
- THRIVE
- Health Education Support Program
Treatment groups
Sponsors and collaborators
Dana-Farber Cancer Institute
Lead sponsor
National Cancer Institute (NCI)
Collaborator
Case Western Reserve University
Collaborator
University of Pittsburgh
Collaborator