Test of Target Engagement of Ambiguity Aversion

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-60
SponsorNorthwestern University

About this trial

The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.

Eligibility criteria

Qualifiers

Ages 25 to 60

Right-handed

Ability to read and write English

Capacity to provide informed consent

Disqualifiers

Personal history of psychosis, mania, or hypomania

Personal history of autism spectrum disorder

IQ < 80 as determined by the Wechsler Test of Adult Reading

Head injury with greater than 120 seconds loss of consciousness

Trial design

Treatments tested in this trial

  • Uncertainty-focused single session intervention
  • Maintaining a healthy lifestyle single session intervention

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Northwestern University

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator