Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age18-50
SponsorThe University of Hong Kong
About this trial
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.
Eligibility criteria
Qualifiers
Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were < 18 years old.
> 18 years old to 50 years old
Cancer in remission for at least 2 years
Disqualifiers
Unable to ejaculate by masturbation to provide semen samples
Cryptorchidism, testicular cancer, history of vasectomy
On testosterone replacement therapy
Refusal to join the study
Trial design
Treatments tested in this trial
- Hormonal profile
- Semen analysis
- Questionnaire
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
The University of Hong Kong
Lead sponsor
Queen Mary Hospital, Hong Kong
Collaborator
Prince of Wales Hospital, Shatin, Hong Kong
Collaborator
Hong Kong Children's Hospital
Collaborator
Source ClinicalTrials.gov