Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorJohns Hopkins Bloomberg School of Public Health

About this trial

The findings from previous recent randomized controlled trials of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections, diarrheal disease, and stunting among young children in intervention households, and had significant sustained impacts on handwashing with soap behaviors and improved water quality 12 months post intervention. Therefore, the investigators next step in the transition to scale is to: (1) To tailor the CHoBI7 program for delivery in rural health facilities and market test the CHoBI7 Program to determine the feasibility of providing a modified water, sanitation, and hygiene (WASH) package with only a soapy water bottle and chlorine tablets in both urban and rural settings through formative research and engagement of key stakeholders (Formative Research Phase); and (2) To evaluate the effectiveness of delivering the CHoBI7 program in district hospitals and sub-district health complexes in rural areas in terms of increases in WASH behaviors and decreases in diarrheal disease by conducting a randomized controlled trial (RCT) (Intervention Implementation and Evaluation Phase).

Eligibility criteria

Qualifiers

Diarrhea patients presenting with three or more loose stools over a 24h period

Having no running water inside of the patient's home

Plan to reside in current residence for the next 3 months

Have a child <5 years in the patient's household

Disqualifiers

No one will be excluded because of age, sex, religion, or sexual preference

Trial design

Treatments tested in this trial

  • Standard Recommendation
  • CHoBI7 Scale-Up Program

Treatment groups

1,600 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Johns Hopkins Bloomberg School of Public Health

Lead sponsor

Research Training and Management International (RTMI)

Collaborator

United States Agency for International Development (USAID)

Collaborator

GiveWell

Collaborator