Testing of a New Rapid Antigen Test for Plague in Ituri, Democratic Republic of the Congo.
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age5+
SponsorInstitute of Tropical Medicine, Belgium
About this trial
This study is being done to learn more about the disease in Ituri and to evaluate a new rapid test that may help doctors find the disease more quickly. This research includes characterisation of clinical presentations and pathology of plague, as well as identification of circumstances that may increase the risk of infection. Biological samples collected include blood, mouth swab, saliva, a bubo aspirate and a sputum sample (the latter only in case of plague in the lungs). These samples will be used to test the performance of the new rapid study test.
Eligibility criteria
Qualifiers
All participants (aged ≥5 year old) within Rethy, Logo and Aru health zones, presenting with possible symptoms of bubonic and/or pneumonic plague according to WHO definition
Willing to provide voluntary consent (or voluntary assent and parental consent in case of minors.
Disqualifiers
Participants not eligible, able, or willing to undergo study procedures
Children <5 years of age
Participants on antibiotic treatment ≥48h prior to recruitment
Trial design
Treatments tested in this trial
- Not listed
Trial groups
300 Participants
are grouped into 1 trial groupSponsors and collaborators
Institute of Tropical Medicine, Belgium
Lead sponsor
Institut Pasteur
Collaborator
Université Paris-Saclay
Collaborator
Centre de Recherche en Maladies Tropicales de L'Ituri (CRMT)
Collaborator
Institut National pour la Recherche Biomedicale (INRB)
Collaborator
Source ClinicalTrials.gov