Texture and Color Enhancement Imaging (TXI) for Inflammation Assessment in Patients With Inflammatory Bowel Diseases

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Ulm

About this trial

In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.

Eligibility criteria

Qualifiers

Histologically confirmed inflammatory bowel disease (ulcerative colitis or Crohn's disease)

Age ≥ 18 years

Disqualifiers

Post (procto-) colectomy

Endoscopically impassable stenosis in the left hemi-colon

ASA status > 2 points

BBPS < 6 points (or < 2 points per segment)

Trial design

Treatments tested in this trial

  • TXI mode vs. WLE mode

Treatment groups

80 Participants
are divided into 1 treatment group

Sponsors and collaborators