The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Trident needle combined with three different aspiration techniques (dry-suction, wet-suction, and slow-pull) in Endoscopic ultrasound-guided fine-needle biopsy for solid pancreatic lesions.
(Before the trial, subjects must meet all of the requirements listed below in order to be enrolled)
18-80 years old (inclusive), male and female;
patients with pancreatic solid mass > 1cm detected by CT/MRI/PET-CT or EUS and requiring EUS-FNB diagnosis.
written informed consent was obtained.
(Before the trial, participants could not be enrolled if they met any of the following requirements)
contraindications to endoscopy, such as severe cardiovascular and cerebrovascular diseases;
bleeding coagulation dysfunction (prothrombin international normalized ratio ≥1.5, platelet count ≤ 50 000) or use of antiplatelet drugs;
confirmed pregnancy or possible pregnancy;
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Treatment groupsSee each treatment group below.