The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRoyal College of Surgeons, Ireland
About this trial
The ACHILLS Trial is a multicentre randomised controlled feasibility study comparing partial calcanectomy with and without the use of an antibiotic-impregnated bone graft substitute (Cerament G) for treating calcaneal osteomyelitis, specifically on wound healing rates, re-infection, and overall efficacy in a sample of 30 patients over a one-year period.
Eligibility criteria
Qualifiers
18 and over
Undergoing partial calcanectomy
Patients with Type1 or Type 2 Diabetes
Patients will be stratified by Pulse status and eGFR
Disqualifiers
Patients unfit for surgery
Patients unable to provide informed consent
Patients with overwhelming sepsis that require major amputation
Patients with hypersensitivity to aminoglycosides
Trial design
Treatments tested in this trial
- Cerament G
- Standard Surgical Managment
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov