About this trial
In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical stimulation (WPHF NMES) in various populations. The investigators will use WPHF NMES contractions as a model to gain insights into the mechanisms underlying muscle cramps, restless legs syndrome or stroke-induced spasticity as there is evidence that they share common underlying mechanisms. The investigators will then use WPHF NMES as a training modality to improve plantar flexor neuromuscular function in stroke patients by taking advantage of their motoneuronal hyperexcitability.
Eligibility criteria
Qualifiers
Diagnosis of first-ever stroke (ischemic or hemorrhagic) with unilateral motor deficits from at least 6 months. Stroke will have to be confirmed from medical records and/or radiological imaging (CT scan or MRI)
Inadequate ankle control during gait defined as ankle dorsiflexion less than 5° during stance phase and 0° during swing phase; 0° = ankle neutral position)
Passive range of motion of ankle dorsiflexion at least to neutral position
Ability to walk at least 10 m with or without assistive devices
Disqualifiers
None
Trial design
Treatments tested in this trial
- wide pulse high frequency neuromuscular electrical stimulation training
Treatment groups
Sponsors and collaborators
University of Lausanne
Lead sponsor
Swiss National Science Foundation
Collaborator