This study is designed as a randomised multicentric parallel group pragmatic trial of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK) in corneal endothelial decompensation. the purpose is to compare the clinical and patient reported outcomes of both therapies across a broad range of indications.
Fuchs Endothelial Dystrophy (FED);
Bullous Keratopathy (BK);
Other miscellaneous causes of endothelial dysfunction including decompensation of a previous corneal graft;
Pseudophakic (post cataract surgery);
Inability to provide informed consent;
Patients unable to attend the proposed follow up;
Inclusion of the fellow eye in the study;
Complex surgery combined with multiple pathologies (i.e., glaucoma surgery);
University Hospital, Antwerp
Lead sponsor
Belgium Health Care Knowledge Centre
Collaborator