About this trial
1. To evaluate the clinical outcomes of ultrasound-guided thermal ablation and thyroid surgery for the treatment of papillary thyroid carcinoma; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of papillary thyroid carcinoma;
Eligibility criteria
Qualifiers
patients age between 18 and 80 year old, both sex
papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
the largest diameter ≤2.0 cm
no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, nech and chest CT
Disqualifiers
patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
history of neck radiation
history of thyroid surgery
coagulation disorder
Trial design
Treatments tested in this trial
- thyroid surgery
- ultrasound-guided thermal ablation