The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorBeijing Tsinghua Chang Gung Hospital

About this trial

This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction. The study aims to assess the safety, efficacy, and functional improvements following these transplant procedures, utilizing donor tissues to restore joint function and alleviate pain in individuals with severe knee damage. Participants will undergo the transplantation procedure and be monitored for post-operative recovery, complications, and long-term outcomes, including joint stability and mobility. The study seeks to provide valuable insights into the effectiveness of these advanced surgical techniques for knee joint repair.

Eligibility criteria

Qualifiers

Aged 18-50 years

Clinical diagnosis of symptomatic meniscal deficiency and anterior cruciate ligament injury (complete rupture or severe damage)

Failure of conservative treatment (e.g., physical therapy, analgesia) for ≥6 months

Stable knee joint (no ligamentous instability confirmed via clinical exam and MRI)

Disqualifiers

Severe tibiofemoral osteoarthritis (Kellgren-Lawrence grade ≥3)

History of prior knee infection or septic arthritis

Inflammatory arthritis (e.g., rheumatoid arthritis, gout)

BMI ≥35 kg/m²

Trial design

Treatments tested in this trial

  • bone-patellar tendon-bone or meniscus allograft transplantation techniques
  • Quasi-anatomical meniscus allograft transplantation

Treatment groups

200 Participants
are divided into 3 treatment groups

Locations

This trial has no locations