About this trial
This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction. The study aims to assess the safety, efficacy, and functional improvements following these transplant procedures, utilizing donor tissues to restore joint function and alleviate pain in individuals with severe knee damage. Participants will undergo the transplantation procedure and be monitored for post-operative recovery, complications, and long-term outcomes, including joint stability and mobility. The study seeks to provide valuable insights into the effectiveness of these advanced surgical techniques for knee joint repair.
Eligibility criteria
Qualifiers
Aged 18-50 years
Clinical diagnosis of symptomatic meniscal deficiency and anterior cruciate ligament injury (complete rupture or severe damage)
Failure of conservative treatment (e.g., physical therapy, analgesia) for ≥6 months
Stable knee joint (no ligamentous instability confirmed via clinical exam and MRI)
Disqualifiers
Severe tibiofemoral osteoarthritis (Kellgren-Lawrence grade ≥3)
History of prior knee infection or septic arthritis
Inflammatory arthritis (e.g., rheumatoid arthritis, gout)
BMI ≥35 kg/m²
Trial design
Treatments tested in this trial
- bone-patellar tendon-bone or meniscus allograft transplantation techniques
- Quasi-anatomical meniscus allograft transplantation