This study will include 246 patients with ovarian reserve dysfunction (DOR), who will be randomly divided into a treatment group and a control group, with 123 patients in each group. The treatment group will receive electro-thumbtack needle treatment, while the control group will receive placebo electro-thumbtack needle treatment. Both groups will receive a treatment course of 3 menstrual cycles. This study evaluates the effect of electrocautery on the live birth rate of patients with DOR.
The age range is 18-40 years old;
Meets the diagnostic criteria for DOR as follows: ① AMH<1.1 ng/ml; ② 10 U/L < FSH < 25U/L or FSH/LH > 3.6; ③ The total number of follicles (AFC) in both basal sinuses is less than 7. If any two of the above criteria (①②③) are met, it can be diagnosed as DOR.
At least one side of the patient's fallopian tube is unobstructed;
The semen routine examination of the patient's spouse is normal;
Chromosomal or genetic abnormalities in either the female or male partner;
Women with blocked fallopian tubes on both sides;
Have a history of ovarian surgery, such as ovarian teratoma or ovarian chocolate cyst surgery;
The female party suffers from uncorrected endocrine disorders such as simple hyperthyroidism or hypothyroidism, hyperprolactinemia, and pancreatic islet dysfunction;
Huazhong University of Science and Technology
Lead sponsor
Tongji Hospital
Sponsor institution