The Correlation Between Red Cell Transfusion and Complications of Prematurity

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-7
SponsorClinical Hospital Center Rijeka

About this trial

The aim of this clinical trial is to learn if there is a correlation between the erythrocyte transfusion in the early neonatal period in premature infants and early and late complications of prematurity. The main questions it aims to answer are:

* Do premature infants who receive blood transfusions within their first month of life have a higher risk of early prematurity complications, such as retinopathy of prematurity, necrotising enterocolitis, bronchopulmonary dysplasia, and intraventricular haemorrhage? * Do premature infants who receive blood transfusions during their first month of life have worse neurological and neurodevelopmental outcomes than those who do not? The first part of the study is retrospective, using data collected from participants' histories. The second part is prospective, evaluating neurological and neurodevelopmental outcomes at the age of six years.

Eligibility criteria

Qualifiers

all children born as premature infants <32. weeks of gestation in Clinical Hospital Centre Rijeka from June 2018. to December 2021. (and who will be on September 2025. six years old)

signed informed consent

Disqualifiers

genetic syndromes, severe congenital anomalies

Trial design

Treatments tested in this trial

  • Wechsler Intelligence Test, performed by educated psychologists

Treatment groups

128 Participants
are divided into 1 treatment group