The Effect of Adding an IPACK Block to the Adductor Canal Block on Total Knee Arthroplasty Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorAydin Adnan Menderes University

About this trial

Total knee arthroplasty (TKA) is a frequently performed major orthopedic surgery, where most patients experience severe postoperative pain. Pain-related delays in patient mobilization can lead to thromboembolism, deep vein thrombosis, surgical site infection, and increased risk of hospital-acquired infections due to prolonged hospital stay. Optimal postoperative knee analgesia is crucial not only for patient comfort and satisfaction but also for accelerating mobilization, functional recovery, and discharge from the hospital. To facilitate early ambulation and superior performance, multimodal analgesia and motor-sparing blocks are increasingly utilized

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients with written informed consent

Patients over 18 years old undergoing elective total knee arthroplasty surgery

Patients with ASA I-II-III

Patients receiving spinal anesthesia

Disqualifiers

Revision knee arthroplasty and bilateral total knee arthroplasty

Liver or kidney failure

Patients under 18 years old

Patients receiving general anesthesia

Trial population

Once eligibility is confirmed, patients will receive complete oral and written information about the study. Informed consent will be obtained before randomization and study-specific procedures.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • rescue analgesia

    Other intervention

    . If NRS is 4 or higher in the postoperative recovery room, 100 mg of intravenous tramadol will be administered as rescue analgesia

  • Adductor Canal Block

    Procedure/Surgery

    For Group I, after patients are placed in the supine position, a linear ultrasound probe (13-6 MHz) will be used to identify the superficial femoral artery in the short axis, lateral to the Sartorius muscle, and anterior to the adductor magnus muscle in the adductor canal. A 22-gauge × 100 mm needle (Braun® Stimuplex) will be inserted in-plane laterally to medially under sterile conditions, and 20 mL of 0.5% bupivacaine will be injected after negative aspiration.

  • Adding an IPACK Block to the Adductor Canal Block

    Procedure/Surgery

    For Group II, 20 mL of 0.25% bupivacaine will be injected into the Adductor Canal after spinal anesthesia. With the knee flexed, a convex probe (3.5-6 MHz) will be placed in the popliteal region to identify the popliteal artery in the short axis. The ultrasound probe will be moved distally after the common peroneal and tibial nerves are identified. The probe will be gradually moved towards the popliteal fossa until the popliteal vessels are identified superficially. The ultrasound probe will be moved to the level where the femoral condyles merge with the femoral shaft. The popliteal artery, tibial and peroneal nerves will be visualized to identify the space between the femur and the popliteal artery. In the area known as iPACK, a 22-gauge × 100 mm needle (Braun® Stimuplex) will be inserted in-plane laterally to medially, and 20 mL of 0.25% bupivacaine will be injected after negative aspiration.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Adductor Canal Block2 interventions
Group B: Adding an IPACK Block to the Adductor Canal Block2 interventions

Trial outcomes

Primary outcomes

1

The primary outcome will be the comparison of discharge times between patients undergoing total knee arthroplasty who receive an adductor canal block with and without the addition of an iPACK block.

Total Knee Arthroplasty surgery results in shorter hospital stays

Time frame
Until discharge after surgery(Up to 6 days after the surgery)

Secondary outcomes

1

The secondary outcome will be the assessment of whether the addition of an iPACK block to the adductor canal block reduces postoperative opioid consumption and pain scores by 50%, which will be considered significant.

İt is a pain intensity determination system based on the system where there person tells a point between 0=(no pain) 10=( unbearable pain) and to describe their pain

Time frame
Acute pain will be assessed after surgery until discharge(Up to 6 days after the surgery)

Other outcomes

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