The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The secondary objectives of this study are to assess the impact of continuous 24-hour intravenous lidocaine infusion on the proportion of patients requiring mechanical ventilation, protection of important organ function during the perioperative period, length of hospital stay, and outcomes within 30 days postoperatively.
Age >18 years, any gender.
Patients suspected of digestive tract perforation or obstruction based on physical examination, confirmed by imaging, requiring emergency surgical treatment.
The anesthesia method is general anesthesia
I or the patient's family have carefully read and signed the informed consent form
Have a history of local anesthesia drug allergy
Pregnant patients
Patients receiving renal replacement therapy
Patients with arrhythmias or heart failure (second or third-degree atrioventricular block or left ventricular ejection fraction（LVEF）
Shanghai Zhongshan Hospital
Lead sponsor
The Affiliated Hospital of Xuzhou Medical University
Collaborator
West China Hospital
Collaborator