About this trial
Controlled hypotension is currently used in spinal surgery to reduce bleeding at the surgical site, improve the surgeon's visibility, and decrease intraoperative blood loss. Although controlled hypotension is considered a beneficial method from a surgical perspective, it is important to be cautious about its side effects. One such side effect is cerebral perfusion insufficiency, which can be managed by monitoring cerebral circulation through regional cerebral oxygen saturation (rSO2).
The aim of this study is to compare the effects of controlled hypotension at specific MAP ranges on cerebral oxygen saturation.
Eligibility criteria
Qualifiers
Aged 18-65 years
ASA I-III risk group
BMI between 18-40
Baseline blood pressure below 140/90 mmHg
Disqualifiers
Below 18 or above 65 years old
Advanced comorbidities
ASA IV or higher
Baseline blood pressure above 140/90 mmHg
Trial design
Treatments tested in this trial
- MAP 55-65 mmHg
- MAP 66-75 mmHg