The Effect of Controlled Hypotension

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAnkara Etlik City Hospital

About this trial

Controlled hypotension is currently used in spinal surgery to reduce bleeding at the surgical site, improve the surgeon's visibility, and decrease intraoperative blood loss. Although controlled hypotension is considered a beneficial method from a surgical perspective, it is important to be cautious about its side effects. One such side effect is cerebral perfusion insufficiency, which can be managed by monitoring cerebral circulation through regional cerebral oxygen saturation (rSO2).

The aim of this study is to compare the effects of controlled hypotension at specific MAP ranges on cerebral oxygen saturation.

Eligibility criteria

Qualifiers

Aged 18-65 years

ASA I-III risk group

BMI between 18-40

Baseline blood pressure below 140/90 mmHg

Disqualifiers

Below 18 or above 65 years old

Advanced comorbidities

ASA IV or higher

Baseline blood pressure above 140/90 mmHg

Trial design

Treatments tested in this trial

  • MAP 55-65 mmHg
  • MAP 66-75 mmHg

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators