The Effect of Distal Versus Proximal iPACK on Pain After Total Knee Arthroplasty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorComenius University

About this trial

Total knee arthroplasty (TKA) often results in significant postoperative pain, which can hinder recovery despite advances in surgical and anesthetic techniques. Traditional pain management methods like femoral nerve blocks may impair motor function, delaying rehabilitation. The iPACK block, targeting the posterior knee without affecting motor control, offers a promising alternative. This study aims to compare the effectiveness of two iPACK block approaches-proximal (at the distal femoral shaft) and distal (between the femoral condyles)-in managing postoperative pain in TKA patients. In a double-blind, randomized controlled trial with 120 participants, pain scores, opioid use, and time to rescue analgesia will be assessed. The hypothesis is that the distal iPACK block provides superior pain relief, potentially improving patient outcomes and recovery.

Eligibility criteria

Qualifiers

Age between 18 and 80 years

Patients undergoing primary unilateral total knee arthroplasty (TKA) for osteoarthritis

Ability to understand and sign informed consent

American Society of Anesthesiologists (ASA) classification I-III

Disqualifiers

Refusal to participate or failure to sign informed consent

Bilateral or revision TKA

Partial or unicondylar knee replacement

Severe knee deformity (flexion, varus, or valgus >30°)

Trial design

Treatments tested in this trial

  • distal iPACK
  • proximal iPACK

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators