About this trial
Total knee arthroplasty (TKA) often results in significant postoperative pain, which can hinder recovery despite advances in surgical and anesthetic techniques. Traditional pain management methods like femoral nerve blocks may impair motor function, delaying rehabilitation. The iPACK block, targeting the posterior knee without affecting motor control, offers a promising alternative. This study aims to compare the effectiveness of two iPACK block approaches-proximal (at the distal femoral shaft) and distal (between the femoral condyles)-in managing postoperative pain in TKA patients. In a double-blind, randomized controlled trial with 120 participants, pain scores, opioid use, and time to rescue analgesia will be assessed. The hypothesis is that the distal iPACK block provides superior pain relief, potentially improving patient outcomes and recovery.
Eligibility criteria
Qualifiers
Age between 18 and 80 years
Patients undergoing primary unilateral total knee arthroplasty (TKA) for osteoarthritis
Ability to understand and sign informed consent
American Society of Anesthesiologists (ASA) classification I-III
Disqualifiers
Refusal to participate or failure to sign informed consent
Bilateral or revision TKA
Partial or unicondylar knee replacement
Severe knee deformity (flexion, varus, or valgus >30°)
Trial design
Treatments tested in this trial
- distal iPACK
- proximal iPACK