About this trial
Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating. The physical and cognitive decrements associated with dehydration have been widely researched, however the effect of dehydration on metabolism is lesser known. As climate change is causing temperatures to rise, and metabolic diseases such as type 2 diabetes are more common, the effect of dehydration on metabolism, specifically glycemic response to meals, needs to be established for future recommendations in clinical, environmental and athletic settings.
Therefore, the aim of this study is to investigate the effect of acute exercise-induced dehydration on subsequent metabolic responses to feeding (i.e. glycaemia and insulinaemia).
Eligibility criteria
Qualifiers
Male or female
Generally fit and healthy
Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week
Disqualifiers
< 18 or > 45
Any health condition that may affect study outcomes (e.g., endocrine/liver/renal/cardiovascular disease)
Any morbidity that affects ability to cycle
Smoker or vaper
Trial design
Treatments tested in this trial
- Water intake
- Water restriction
Treatment groups
Sponsors and collaborators
Loughborough University
Lead sponsor
National Institute for Health Research Leicester Biomedical Research Centre
Collaborator