The Effect of Hydration on Postprandial Metabolic Responses

ConditionGlycaemia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorLoughborough University

About this trial

Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating. The physical and cognitive decrements associated with dehydration have been widely researched, however the effect of dehydration on metabolism is lesser known. As climate change is causing temperatures to rise, and metabolic diseases such as type 2 diabetes are more common, the effect of dehydration on metabolism, specifically glycemic response to meals, needs to be established for future recommendations in clinical, environmental and athletic settings.

Therefore, the aim of this study is to investigate the effect of acute exercise-induced dehydration on subsequent metabolic responses to feeding (i.e. glycaemia and insulinaemia).

Eligibility criteria

Qualifiers

Male or female

Generally fit and healthy

Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week

Disqualifiers

< 18 or > 45

Any health condition that may affect study outcomes (e.g., endocrine/liver/renal/cardiovascular disease)

Any morbidity that affects ability to cycle

Smoker or vaper

Trial design

Treatments tested in this trial

  • Water intake
  • Water restriction

Treatment groups

16 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Loughborough University

Lead sponsor

National Institute for Health Research Leicester Biomedical Research Centre

Collaborator