The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorPeking University Third Hospital

About this trial

The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are:

Is it possible that the device can treat postoperative olfactory dysfunction in patients with chronic sinusitis? Compared to the conventional device, how efficient is the modified olfactory training device for treating postoperative olfactory dysfunction in patients with chronic sinusitis?

Eligibility criteria

Qualifiers

A diagnosis of CRSsNP based on the European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS20).

The duration after endoscopic sinus surgery is 3months.

Olfactory dysfunction confirmed with the Sniffin's Sticks psychophysical test (TDI score≦30.5) .

Willingness to participate in this study and sign the informed consent form (ICF).

Disqualifiers

Patients with olfactory impairment due to traumatic, congenital, toxic/drug-induced causes, tumors, or post-upper respiratory infections.

Lund-Mackay olfactory cleft score > 0.

Patients with severe comorbidities, such as malignant tumors.

Current or planned pregnancy prior to the end of study.

Trial design

Treatments tested in this trial

  • Conventional olfactory training device
  • Modified olfactory training device
  • Budesonide irrigation

Treatment groups

213 Participants
are divided into 3 treatment groups