The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversity of Health Sciences Lahore

About this trial

Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus while delayed post operative complications are mostly seen on the distal surface of second molar due to distal bone loss which include prolonged sensitivity due to increased periodontal pocket depth, gingival recession and root exposure.

When PRF clot is given in wound, it causes alterations of the cellular ratios in the wound blood clot, leading to replacement of blood cells with Platelets and growth factors stimulating all phases of healing which will improve the immidiate and delayed post operative complications The purpose of present study is to compare the clinical outcomes in the treatment of senstivity and periodontal pockets at the distal aspect of second molar following surgical extraction of impacted third molar using PRF or Blood clot alone.

Eligibility criteria

Qualifiers

Impacted third molar (as per Operational Definition) with fully erupted second molars bilaterally.

Impacted Third molar with Class 2 and Level B according to Pell and Gregory's classification (Annexure B) with mesioangular or horizontal angulation of impaction

Periodontal pocket depth > 4mm and Clinical attachment loss > 1mm at distal side of second molar

Age 18-40 years, both genders.

Disqualifiers

Any Systemic Disease i.e. Uncontrolled Diabetes mellitus, Uncontrolled hypertension, Ischemic heart disease, bleeding disorders, Autoimmune diseases or immunocompromised patients

Decayed or recommended for extraction second molars on either side.

Allergic to Amoxicillin to standardize Antibiotic therapy protocol.

Untreated periodontal condition.

Trial design

Treatments tested in this trial

  • Platelet rich fibrin

Treatment groups

56 Participants
are divided into 2 treatment groups