About this trial
The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical procedure that makes a new ACL using the patient's own tendon). Cryoneurolysis is an approved process of applying extreme cold temperatures to targeted nerves in order to decrease or eliminate pain. . If you take part in the research, you will be randomly assigned (assigned by chance, like a flip of a coin) to Group A (standard care) or Group B (standard care plus Cryoneurolysis). Participants in both groups will undergo standard ACL reconstruction and receive standard preoperative and postoperative pain management. Participants in Group B only will also receive a standard treatment of Cryoneurolysis to their surgical knee within 7-10 days before their scheduled surgery. Participants in both groups (A \& B) will be asked to bring their remaining postoperative pain medication to their postoperative follow-up appointments for review by study personnel. Participants will also be asked to complete a survey about their knee activity, function and symptoms at these appointments. Your time in the study will last until the completion of the 12-week postoperative follow-up appointment.
Eligibility criteria
Qualifiers
- Patients aged 14 and over
Patients who are patients within the PI's practice
Patients who can speak and read English
Patients undergoing autograft ACL reconstruction.
Disqualifiers
- Under the age of 14
Non-English speaking/reading patients
Patients with Reynauds' syndrome
Patients with skin disorders or hypo-vascularity
Trial design
Treatments tested in this trial
- Cryoneurolysis
Treatment groups
Sponsors and collaborators
Virtua Health, Inc.
Lead sponsor
Pacira Pharmaceuticals, Inc
Collaborator