The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNational Taiwan University Hospital
About this trial
This project is a randomized controlled clinical research design, The hypothesis P-I-C-O of the study is: For adult patients in the Taipei City and New Taipei City communities who have suffered sudden non-traumatic death and have been resuscitated by advanced paramedics, the intervention group that receives combined drug treatment (epinephrine, vasopressin, methylprednisolone) has a better rate of sustained recovery of spontaneous circulation (ROSC) (primary outcome) and long-term survival status (secondary outcomes) compared to the control group that receives single drug treatment (epinephrine).
Eligibility criteria
Qualifiers
Adult patients (aged >= 18 )
Out-of-hospital cardiac arrest in the studied regions
Treated by paramedics authorized and capable of giving prehospital medication
Disqualifiers
OHCA with traumatic etiology
Obvious signs of death like decapitation, rigor mortis, livor mortis, decomposition, etc.
DNR (Do Not Resuscitation) or termination of resuscitation requested by the family
Patients with known or suspected pregnancy
Trial design
Treatments tested in this trial
- Combination group
- Standard group
Treatment groups
1,344 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov