The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery

ConditionsAcute Kidney Injury Pediatric Cardiac Surgery

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

AgeUp to 7

SponsorSeoul National University Hospital

About this trial

The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following cardiopulmonary bypass.

Eligibility criteria

Qualifiers

Pediatric patients under 7 years of age undergoing cardiac surgery with cardiopulmonary bypass

Preoperative serum albumin level of 4.0 g/dL or lower

Disqualifiers

abnormal preoperative creatinine level

history of dialysis

liver dysfunction

diabetes

Trial design

Treatments tested in this trial

Albumin solution
Crystalloid solutions

Treatment groups

190 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Seoul National University Hospital

Lead sponsor

Source ClinicalTrials.gov