About this trial
The goal of this clinical trial is to compare the effect of pulmonary vein isolation on atrial function between pulse-field and cryoablation in patients over the age of 18 with paroxysmal atrial fibrillation. The main question it aims to answer is:
• Is catheter ablation energy (pulse field ablation) revealing a better preservation of the atrial function architecture than with conventional catheter ablation technologies ?
Participants will performed 2 IRMs with injection and completed Quality of Life Questionnaires. They participate in the study for 4 months.
Researchers will compare 2 arms:
* Pulse-Field Ablation * Cryoablation
Eligibility criteria
Qualifiers
Patient age ≥ 18
Established diagnosis of paroxysmal fibrillation, with a I/IIa/IIb indication for catheter ablation (ESC 2020 guidelines)
Episode of AF documented by ECG within the last 12 months
Patient able to give written informed consent
Disqualifiers
Non-paroxysmal atrial fibrillation
Contraindication to oral anticoagulation
Intracardiac thrombus
Previous ablation in the left atrium
Trial design
Treatments tested in this trial
- Pulmonary vein isolation by pulse field ablation
- Pulmonary vein isolation by cryoablation