The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorUniversity of Central Florida
About this trial
The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are:
Does the menstrual cycle influence neutrophil recruitment and adhesion after resistance exercise? Does the menstrual cycle affect markers of muscle damage and functional recovery? Researchers will compare three menstrual phases (early follicular, late follicular, and mid-luteal) to see if immune responses and recovery outcomes differ across these phases.
Participants will:
Complete resistance exercise protocols across three different menstrual cycle phases.
Provide blood samples to assess immune cell activation and muscle damage markers.
Track sleep, mood, and recovery with questionnaires and wear an accelerometer.
Eligibility criteria
Qualifiers
Women between the ages of 18 and 40.
Must weigh at least 110 pounds.
Healthy as determined by medical history, physical activity readiness, and menstrual cycle questionnaires.
Actively resistance training for at least 6 months (minimum of 3 resistance training sessions per week, with at least one lower body session).
Disqualifiers
Do not give consent to participate.
Have been determined unfit to participate based on medical or activity history (using health questionnaires).
Currently take prescription or over-the-counter medication that could affect the study results.
Have a chronic illness requiring medical care.
Trial design
Treatments tested in this trial
- Resistance exercise
- Menstrual Cycle Phases
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov