The Effective Blood Concentration of Ciprofol
ConditionThyroid Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorPeking University Shenzhen Hospital
1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3. The patients' pain and cognition are followed up after surgery.
Patients aged 18-65 years
Scheduled for elective thyroidectomy
ASA physical status classification I-II
Willing to participate and providing written informed consent
Recent use of sedatives or opioid analgesics
Severe hepatic or renal dysfunction defined as:Child-Pugh class C (score ≥10), Creatinine clearance <35 mL/min ,Requiring preoperative dialysis
Significant cardiovascular comorbidities
Body mass index ≥35 kg/m² or <18.5 kg/m²