This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis.
The primary objective is to determine whether the supplement improves osteoarthritis-related symptoms.
The supplement will be compared with a placebo.
Participants will:
* take the supplement and placebo for 4 weeks each, one at a time; * complete validated questionnaires (6 times online) * perform three performance-based physical tests (6 times online) * provide a urine sample
Aged ≥ 18
Diagnosis of osteoarthritis in knee or hip
Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours
Lequesne's Functional Index (LFI) score ≥ 7
Pregnant and breastfeeding
Autoimmune disease such as rheumatoid arthritis, gout, lupus
Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage
Expectation of surgery