The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorQueen Savang Vadhana Memorial Hospital, Thailand

About this trial

The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days starting the same day as tocolytic therapy, in pregnant women diagnosed with preterm labor at gestational age 24-33 weeks .Primary Outcome is the rate of pregnancy prolongation beyond 7 days after initiation of tocolytic therapy.

Eligibility criteria

Qualifiers

None

Disqualifiers

Age under 18 years or 35 years and older

Incomplete course of Gynoflor® (less than 6 days of use)

Presence of contraindications to tocolysis

Preterm premature rupture of membranes (PPROM)

Trial design

Treatments tested in this trial

  • Gynoflor

Treatment groups

80 Participants
are divided into 2 treatment groups

Locations

This trial has no locations